师资队伍

贺洪飞

发布日期:2023-09-13 点击:

贺洪飞

贺洪飞,理学博士,副研究员,硕士研究生导师

邮箱:hehongfei0609@163.com

研究方向:核酸检测技术、DNA自组装技术、核酸纳米材料制备

个人简介

四川大学本硕博及博后,主要从事DNA纳米材料、DNA信号放大技术和核酸扩增技术研究,近年来主要聚焦核酸等温扩增技术开发及其在靶标检测和DNA纳米材料上的应用,关注核酸检测中靶标特异性信号的放大和输出策略建立,注重核酸扩增技术和DNA自组装技术在有机化学、医学、生物领域的交叉融合。在Analytical Chemistry、Biosensors & Bioelectronics、Clinical Chemistry、Talanta、Journal of Materials Chemistry B等生化分析、材料领域的SCI期刊以第一作者、共同一作或通讯作者发表10余篇论文。

获批课题(4项)

(1)国家自然科学基金委,青年科学基金项目,自模板引物诱导的枝联核酸等温扩增构建DNA水凝胶,2024-01 至 2026-12, 30.0万元,项目编号:22307014,获批,主持

(2)四川省科学技术厅,应用基础研究,硒核酸用于非洲猪瘟病毒的简便、快速、灵敏、准确、可视化的现场核酸检测研究,2021-04 至 2023-03,10万元,项目编号:2021YJ0487,已结题

(3)南充市科学技术局,国家自然(社会)科学基金项目培育专项,特异性信号筛选和双重放大的超灵敏核酸等温扩增及生物传感,2022-06 至 2024-05,8.0万元,项目编号:22SXZRKX0001,在研,主持

(4)川北医学院,博士启动基金项目(自然科学类),高保真聚合,特异性信号提取和转换的超灵敏核酸等温扩增研究及其在疾病诊断的应用,2021-12 至 2024-12,20.0万元,项目编号:CBY21-QD02,在研,主持

代表性论文(5篇)

(1) Hongfei He, Jianyuan Dai, Zhijuan Duan, Yan Meng, Cuisong Zhou, Yuyin Long, Baozhan Zheng, Juan Du, Yong Guo, and Dan Xiao, Target-catalyzed autonomous assembly of dendrimer-like DNA nanostructures for enzyme-free and signal amplified colorimetric nucleic acids detection, Biosensors & Bioelectronics, 2016, 86, 985−989.

(2) Hongfei He, Jianyuan Dai, Guixiu Dong, Hongli Shi, Fang Wang, Yunran Qiu, Ruoxing Liao, Cuisong Zhou, Yong Guo, and Dan Xiao, Self-replication-assisted rapid preparation of DNA nanowires at room temperature and its biosensing application, Analytical Chemistry, 2019, 91, 3043−3047.

(3) Hongfei He, Guangcheng Luo, Jun Zhang, Ling Tang, Yan Zhou, Bei Hu, Jianyuan Dai and Zhen Huang, Signal extraction, transformation and magnification for ultrasensitive and specific detection of nucleic acids, Analytical Chemistry, 2021, 93, 10611−10618.

(4) Hongfei He, Yan Zhou, Bin Chen, Yi Zhang, Xiaowu Zhong, Lei Xu, Bin Guo, Chong Yin, Xi Zhou, Qingrong Li, Zhen Huang, Guangcheng Luo, and Xiaolan Guo, Nucleic acid amplification with specific signal filtration and magnification for ultrasensitive colorimetric detection, Talanta, 2023, 253, 123978.

(5) Guangcheng Luo, Hongfei He, Dongsheng Wang, Shanshan Liu, Shisu Tian, Miaomiao Chen, Qiang Wang, Changsong Zhao, Zhengwei Leng, Lingmi Hou, and Xiaolan Guo, Tandem repeat generation and novel isothermal amplification based on nonspecific tailing and replication slippage, Clinical Chemistry, 2023, 69, 363–373.(共同一作)

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